Design, synthesis, and pharmacological evaluation of N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as interleukin-1 receptor-associated kinase 4 inhibitors with reduced potential for cytochrome P450 1A2 induction-Reference-Cited by-同舟云学术

Design, synthesis, and pharmacological evaluation of N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as interleukin-1 receptor-associated kinase 4 inhibitors with reduced potential for cytochrome P450 1A2 induction

Published:2023-05 Issue: Volume:87 Page:117302
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Inami Hiroshi^ORCID,Mizutani Tsuyoshi,Watanabe Junko,Hayashida Hisashi,Ito Tomonori,Terasawa Takeshi,Kontani Toru,Yamagishi Hiroaki,Usuda Hiroyuki,Aoyama Naohiro^ORCID,Imamura Emiko,Ishikawa Takeshi

Funder

Astellas Pharma

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference42 articles.

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4. Pyogenic bacterial infections in humans with IRAK-4 deficiency;Picard;Science,2003

5. Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer;OʼNeill;Pharmacol Rev,2009

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