Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors

Published:2011-11 Issue:22 Volume:19 Page:6726-6734
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

He Xiao-Yang,Zou Peng,Qiu Jiayin,Hou Ling,Jiang Shibo,Liu Shuwen,Xie Lan

Funder

the Ministry of Science and Technology in China

the National Science Foundation of China (NSFC)

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. Core Structure of gp41 from the HIV Envelope Glycoprotein

2. Enfuvirtide: the first HIV fusion inhibitor

3. HIV envelope: challenges and opportunities for development of entry inhibitors

4. Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion

5. HIV Entry Inhibitors Targeting gp41: From Polypeptides to Small-Molecule Compounds

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