New inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 7-hydroxycoumarin and monoterpenoid moieties-Reference-Cited by-同舟云学术

New inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 7-hydroxycoumarin and monoterpenoid moieties

Published:2016-11 Issue:21 Volume:24 Page:5573-5581
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Khomenko Tatyana,Zakharenko Alexandra,Odarchenko Tatyana,Arabshahi Homayon John,Sannikova Victoriya,Zakharova Olga,Korchagina Dina,Reynisson Jóhannes,Volcho Konstantin,Salakhutdinov Nariman,Lavrik Olga

Funder

Russian Scientific Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference46 articles.

1. The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily

2. A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.

3. Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target

4. Tyrosyl-DNA Phosphodiesterase 1 Targeting for Modulation of Camptothecin-Based Treatment

5. Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitors

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