Synthesis and bioevaluation study of novel N -methylpicolinamide and thienopyrimidine derivatives as selectivity c-Met kinase inhibitors-Reference-Cited by-同舟云学术

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Synthesis and bioevaluation study of novel N -methylpicolinamide and thienopyrimidine derivatives as selectivity c-Met kinase inhibitors

Published:2018-01 Issue:1 Volume:26 Page:245-256
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Wang Linxiao,Xu Shan,Chen Xiuying,Liu Xiaobo,Duan Yongli,Kong Dejia,Zhao Dandan,Zheng Pengwu,Tang Qidong,Zhu Wufu

Funder

The National Natural Science Funds of China

Natural Science Foundation of Jiangxi, China

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Oncogenic kinase signalling;Blume-Jensen;Nature,2001

2. Met, metastasis, motility and more;Birchmeier;Nat Rev Mol Cell Biol,2003

3. The biology of VEGF and its receptors;Ferrara;Nat Med,2003

4. Development of c-MET pathway inhibitors;Liu;Expert Opin Invest Drugs,2011

5. Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks;Kataoka;Invest New Drugs,2012

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