Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors-Reference-Cited by-同舟云学术

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Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors

Published:2013-11 Issue:22 Volume:21 Page:6893-6909
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Razzaghi-Asl Nima,Firuzi Omidreza,Hemmateenejad Bahram,Javidnia Katayoun,Edraki Najmeh,Miri Ramin

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference51 articles.

1. The Development of New Therapeutics for Alzheimer's Disease

2. Social Cognition: An Early Impairment in Dementia of the Alzheimer Type

3. Boom in the development of non-peptidic β-secretase (BACE1) inhibitors for the treatment of Alzheimer's disease

4. β-Secretase (BACE) as a drug target for alzheimer’s disease

5. Purification and cloning of amyloid precursor protein β-secretase from human brain

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1. Screening Techniques for Drug Discovery in Alzheimer’s Disease;ACS Omega;2024-02-05

2. Synthesis and in-Silico Studies of Some New Thiazole Carboxamide Derivatives with Theoretical Investigation;Polycyclic Aromatic Compounds;2023-08-11

3. Fused 1,4‐Dihydropyridines and Their Corresponding Pyridines: Synthesis, Molecular Modeling and Cholinesterase Inhibition;ChemistrySelect;2023-05-15

4. Virtual screening, molecular docking, and physiochemical analysis of novel 1,3-diphenyl-2-propene-1-one as dual COX-2/5-LOX inhibitors;Letters in Drug Design & Discovery;2022-05-23

5. Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs;European Journal of Medicinal Chemistry;2021-12

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