Rational design, synthesis and biological evaluation of novel multitargeting anti-AD iron chelators with potent MAO-B inhibitory and antioxidant activity

Author:

Jiang Xiaoying,Guo Jianan,Lv Yangjing,Yao Chuansheng,Zhang Changjun,Mi Zhisheng,Shi Yuan,Gu Jinping,Zhou Tao,Bai Renren,Xie Yuanyuan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference57 articles.

1. Drug therapy: Alzheimer's disease;Cummings;N Engl J Med,2004

2. A.s. Association, 2019 Alzheimer's disease facts and figures, Alzheimers & Dementia, 15 (2019) 321–87.

3. Exploring the pathogenesis of Alzheimer disease in basal forebrain cholinergic neurons: converging insights from alternative hypotheses;Chen;Front Neurosci-Switz,2019

4. Intracellular amyloid-β in Alzheimer's disease;LaFerla;Nat Rev Neurosci,2007

5. Regulation of copper and iron homeostasis by metal chelators: a possible chemotherapy for Alzheimer's disease;Robert;Acc Chem Res,2015

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