Discovery of pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors-Reference-Cited by-同舟云学术

Discovery of pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors

Published:2012-01 Issue:1 Volume:20 Page:69-85
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Kendall Jackie D.,O’Connor Patrick D.,Marshall Andrew J.,Frédérick Raphaël,Marshall Elaine S.,Lill Claire L.,Lee Woo-Jeong,Kolekar Sharada,Chao Mindy,Malik Alisha,Yu Shuqiao,Chaussade Claire,Buchanan Christina,Rewcastle Gordon W.,Baguley Bruce C.,Flanagan Jack U.,Jamieson Stephen M.F.,Denny William A.,Shepherd Peter R.

Funder

Health Research Council of New Zealand

Maurice Wilkins Centre for Molecular Biodiscovery

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. Progress in the Design and Development of Phosphoinositide 3-Kinase (PI3K) Inhibitors for the Treatment of Chronic Diseases

2. PTEN loss in the continuum of common cancers, rare syndromes and mouse models

3. Present and Future of PI3K Pathway Inhibition in Cancer: Perspectives and Limitations

4. A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types

5. Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors

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