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Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease

  • Published:2023-08 Issue: Volume:91 Page:117419
  • ISSN:0968-0896
  • Container-title:Bioorganic & Medicinal Chemistry
  • language:en
  • Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Uliassi ElisaORCID,Bergamini Christian,Rizzardi Nicola,Naldi Marina,Cores Ángel,Bartolini Manuela,Carlos Menéndez J.,Bolognesi Maria Laura

Funder

Gobierno de Espana Ministerio de Ciencia e Innovacion

Ministerio de Ciencia e Innovación

Università di Bologna

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference47 articles.

1. Alzheimer Disease;Knopman;Nat Rev Dis Primers,2021

2. International, A. D. Dementia Statistics. https://www.alzint.org/about/dementia-facts-figures/dementia-statistics/.

3. Reconsideration of Anticholinesterase Therapeutic Strategies against Alzheimer’s Disease;Wang;ACS Chem Neurosci,2019

4. Revisiting the Role of Acetylcholinesterase in Alzheimer’s Disease: Cross-Talk with P-Tau and β-Amyloid;García-Ayllón;Front Mol Neurosci,2011

5. Alzheimer’s disease: the amyloid cascade hypothesis;Hardy;Science,1992
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