Does the combination of optimal substitutions at the C2-, N5- and N8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 adenosine receptors?-Reference-Cited by-同舟云学术

Does the combination of optimal substitutions at the C2-, N5- and N8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 adenosine receptors?

Published:2011-10 Issue:20 Volume:19 Page:6120-6134
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Cheong Siew Lee,Dolzhenko Anton V.,Paoletta Silvia,Lee Evelyn Pei Rong,Kachler Sonja,Federico Stephanie,Klotz Karl-Norbert,Dolzhenko Anna V.,Spalluto Giampiero,Moro Stefano,Pastorin Giorgia

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

1. Adenosine receptors as therapeutic targets

2. Progress in the pursuit of therapeutic adenosine receptor antagonists

3. Adenosine A3 receptors: novel ligands and paradoxical effects

4. A glance at adenosine receptors: novel target for antitumor therapy

5. Recent developments in adenosine receptor ligands and their potential as novel drugs

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