Exploiting differences in caspase-2 and -3 S2 subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors-Reference-Cited by-同舟云学术

Exploiting differences in caspase-2 and -3 S2 subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors

Published:2011-10 Issue:19 Volume:19 Page:5833-5851
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Maillard Michel C.,Brookfield Frederick A.,Courtney Stephen M.,Eustache Florence M.,Gemkow Mark J.,Handel Rebecca K.,Johnson Laura C.,Johnson Peter D.,Kerry Mark A.,Krieger Florian,Meniconi Mirco,Muñoz-Sanjuán Ignacio,Palfrey Jordan J.,Park Hyunsun,Schaertl Sabine,Taylor Malcolm G.,Weddell Derek,Dominguez Celia

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference55 articles.

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4. Design of Caspase Inhibitors as Potential Clinical Agents;Matsui,2009

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