Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors

Published:2013-11 Issue:22 Volume:21 Page:7025-7037
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Goto Taiji,Shiina Akiko,Yoshino Toshiharu,Mizukami Kiyoshi,Hirahara Kazuki,Suzuki Osamu,Sogawa Yoshitaka,Takahashi Tomoko,Mikkaichi Tsuyoshi,Nakao Naoki,Takahashi Mizuki,Hasegawa Masashi,Sasaki Shigeki

Funder

Institute of Materials Structure Science

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

2. Phosphodiesterase Isozymes

3. Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: Advances in the development of specific phosphodiesterase inhibitors

4. Phosphodiesterase-4 as a potential drug target

5. Recent Advances on Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease

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4. Research developments in the syntheses, anti-inflammatory activities and structure–activity relationships of pyrimidines;RSC Advances;2021

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