Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET-Reference-Cited by-同舟云学术

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Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET

Published:2007-01 Issue:2 Volume:15 Page:616-625
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Schou Magnus,Pike Victor W.,Sóvágó Judit,Gulyás Balázs,Gallagher Peter T.,Dobson David R.,Walter Magnus W.,Rudyk Helene,Farde Lars,Halldin Christer

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference44 articles.

1. Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography

2. Pharmacology and Distribution of Norepinephrine Transporters in the Human Locus Coeruleus and Raphe Nuclei

3. Norepinephrine transporter sites are decreased in the locus coeruleus in Alzheimer's disease

4. Role of norepinephrine in the pathophysiology and treatment of mood disorders

5. Reduced Levels of Norepinephrine Transporters in the Locus Coeruleus in Major Depression

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