One-Electron reduction characteristics of N(3)-Substituted 5-fluorodeoxyuridines synthesized as radiation-Activated prodrugs

Author:

Tanabe Kazuhito,Mimasu Youhei,Eto Akira,Tachi Yukihiro,Sakakibara Shingo,Mori Mayuko,Hatta Hiroshi,Nishimoto Sei-ichi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. Chu, E.; Mota, A.; Fogarasi, M. C. In Cancer Principles & Practice of Oncology Vol. 1, 6th Ed.; DeVita, V. T., Jr Hellman, S.; Hellman, Rosenberg, S. A. Ed., Lippincott Williams & Wilkins: Philadelphia 2001, 388.

2. Intrathecal 5-fluoro-2′-deoxyuridine (FdUrd) for the treatment of solid tumor neoplastic meningitis: an in vivo study

3. A photoactivated prodrug

4. Antibody-Catalyzed Prodrug Activation

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