Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate-Reference-Cited by-同舟云学术

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Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate

Published:2014-05 Issue:9 Volume:22 Page:2648-2654
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Fan Jinda,Zhang Xiang,Li Junfeng,Jin Hongjun,Padakanti Prashanth K.,Jones Lynne A.,Flores Hubert P.,Su Yi,Perlmutter Joel S.,Tu Zhude

Funder

National Institute of Mental Health (NIMH)

National Institute of Neurological Disorders and Stroke (NINDS)

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. Development of a cell-based assay for screening of phosphodiesterase 10A (PDE10A) inhibitors using a stable recombinant HEK-293 cell line expressing high levels of PDE10A

2. Isolation and characterization of PDE10A, a novel human 3′, 5′-cyclic nucleotide phosphodiesterase

3. Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

4. Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: Evidence for altered striatal function

5. Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase

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1. Advances in Cyclic Nucleotide Phosphodiesterase-Targeted PET Imaging and Drug Discovery;Journal of Medicinal Chemistry;2021-05-27

2. Challenges on Cyclic Nucleotide Phosphodiesterases Imaging with Positron Emission Tomography: Novel Radioligands and (Pre-)Clinical Insights since 2016;International Journal of Molecular Sciences;2021-04-07

3. Medicinal chemistry strategies for the development of phosphodiesterase 10A (PDE10A) inhibitors - An update of recent progress;European Journal of Medicinal Chemistry;2021-03

4. The chemistry of labeling heterocycles with carbon-11 or fluorine-18 for biomedical imaging;Advances in Heterocyclic Chemistry;2020

5. Advances in the Discovery of PDE10A Inhibitors for CNS-Related Disorders. Part 2: Focus on Schizophrenia;Current Drug Targets;2019-11-13

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