Discovery andw biological evaluation of novel 6,7-disubstituted-4-(2-fluorophenoxy)quinoline derivatives possessing 1,2,3-triazole-4-carboxamide moiety as c-Met kinase inhibitors-Reference-Cited by-同舟云学术

Discovery andw biological evaluation of novel 6,7-disubstituted-4-(2-fluorophenoxy)quinoline derivatives possessing 1,2,3-triazole-4-carboxamide moiety as c-Met kinase inhibitors

Published:2014-11 Issue:22 Volume:22 Page:6438-6452
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Zhou Shunguang,Liao Huimin,Liu Mingmei,Feng Guobing,Fu Baolin,Li Ruijuan,Cheng Maosheng,Zhao Yanfang,Gong Ping

Funder

Program for Innovative Research Team of the Ministry of Education of the People’s Republic of China

Program for Liaoning Innovative Research Team in University (design, synthesis and antitumor activities of novel 4-phenoxyquinoline derivatives as c-Met kinase inhibitors, long-term training of young teachers of Shenyang Pharmaceutical University

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference50 articles.

1. Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

2. Receptor Tyrosine Kinases as Therapeutic Targets the Model of the MET Oncogene

3. Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition

4. Scatter-factor and semaphorin receptors: cell signalling for invasive growth

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