Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin-Reference-Cited by-同舟云学术

Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin

Published:2024-02 Issue: Volume:100 Page:117614
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Rudolph Michael J.,Dutta Arkajyoti^ORCID,Tsymbal Anastasiia M.,McLaughlin John E.,Chen Yang,Davis Simon A.,Theodorous Sophia A.,Pierce Michael,Algava Benjamin^ORCID,Zhang Xiaoyu,Szekely Zoltan,Roberge Jacques Y.,Li Xiao-Ping^ORCID,Tumer Nilgun E.^ORCID

Funder

National Institutes of Health

Publisher

Elsevier BV

Reference51 articles.

1. Ricin poisoning: a comprehensive review;Audi;J Am Med Assoc,2005

2. Pathogenesis of Shiga-toxin producing Escherichia coli;Melton-Celsa;Curr Top Microbiol Immunol,2012

3. The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli;Karmali;J Infect Dis,1985

4. Factors in the emergence of serious human infections associated with highly pathogenic strains of shiga toxin-producing Escherichia coli;Karmali;Int J Med Microbiol,2018

5. RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes;Endo;J Biol Chem,1987

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A fluorescence anisotropy-based competition assay to identify inhibitors against ricin and Shiga toxin ribosome interactions;Analytical Biochemistry;2024-09

2. Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2;ACS Infectious Diseases;2024-06-14