Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex-Reference-Cited by-同舟云学术

Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex

Published:2017-10 Issue:19 Volume:25 Page:5114-5127
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ghosh Arun K.,Brindisi Margherita,Nyalapatla Prasanth R.,Takayama Jun,Ella-Menye Jean-Rene,Yashchuk Sofiya,Agniswamy Johnson,Wang Yuan-Fang,Aoki Manabu,Amano Masayuki,Weber Irene T.,Mitsuya Hiroaki

Funder

National Institutes of Health

US Department of Energy, Basic Energy Sciences, Office of Science

Intramural Research Program of the Center for Cancer Research, National Cancer Institute, National Institutes of Health

Ministry of Education, Culture, Sports, Science, and Technology of Japan

Ministry of Health, Welfare, and Labor of Japan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

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3. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS

4. Demonstration of Sustained Drug-Resistant Human Immunodeficiency Virus Type 1 Lineages Circulating among Treatment-Naïve Individuals

5. Antiretroviral Therapy for the Prevention of HIV-1 Transmission

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