Synthesis of 6-(het) ary Xylocydine analogues and evaluating their inhibitory activities of CDK1 and CDK2 in vitro-Reference-Cited by-同舟云学术

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Synthesis of 6-(het) ary Xylocydine analogues and evaluating their inhibitory activities of CDK1 and CDK2 in vitro

Published:2011-12 Issue:23 Volume:19 Page:7100-7110
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Xiao Chuan,Sun Chao,Han Weiwei,Pan Feng,Dan Zhu,Li Yu,Song Zhi-Guang,Jin Ying-Hua

Funder

National Nature Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference44 articles.

1. Mammalian cyclin-dependent kinases

2. Cell cycle, CDKs and cancer: a changing paradigm

3. Control of cell proliferation in atherosclerosis: insights from animal models and human studies

4. An efficient tool for identifying inhibitors based on 3D-QSAR and docking using feature-shape pharmacophore of biologically active conformation – A case study with CDK2/CyclinA

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