1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin-Reference-Cited by-同舟云学术

1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin

Published:2008-05 Issue:9 Volume:16 Page:4829-4838
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Odlo Kristin,Hentzen Jean,dit Chabert Jérémie Fournier,Ducki Sylvie,Gani Osman A.B.S.M.,Sylte Ingebrigt,Skrede Martina,Flørenes Vivi Ann,Hansen Trond Vidar

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference71 articles.

1. MICROTUBULE POLYMERIZATION DYNAMICS

2. Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle

3. Targeting Microtubules to Inhibit Angiogenesis and Disrupt Tumour Vasculature:Implications for Cancer Treatment

4. Small Molecule Vascular Disrupting Agents: Potential New Drugs for Cancer Treatment

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