New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus

Author:

Samir Mohamed,Ramadan Mohamed,Abdelrahman Mostafa H.,Elbastawesy Mohammed A.I.,Halby Hamada Mohamed,Abdel-Aziz Mohamed,Abuo-Rahma Gamal El-Din A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference38 articles.

1. Thiazolidine-2, 4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities;Aziz;Mol Divers,2021

2. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects;Ibrahim;Eur J Med Chem,2022

3. Recent insight into the biological activities and SAR of quinolone derivatives as multifunctional scaffold;Sharma;Bioorg Med Chem,2022

4. Antimicrobial bacillus: Metabolites and their mode of action;Tran;Antibiotics,2022

5. A review on quinoline derivatives as anti-methicillin resistant staphylococcus aureus (MRSA) agents;Kumar;BMC Chem,2020

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