3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 2: Optimization of the side chains to improve in vitro and in vivo potencies-Reference-Cited by-同舟云学术

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 2: Optimization of the side chains to improve in vitro and in vivo potencies

Published:2010-02 Issue:4 Volume:18 Page:1641-1658
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Asada Masaki,Iwahashi Maki,Obitsu Tetsuo,Kinoshita Atsushi,Nakai Yoshihiko,Onoda Takahiro,Nagase Toshihiko,Tanaka Motoyuki,Yamaura Yoshiyuki,Takizawa Hiroya,Yoshikawa Ken,Sato Kazutoyo,Narita Masami,Ohuchida Shuichi,Nakai Hisao,Toda Masaaki

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference16 articles.

1. A novel inhibitory prostanoid receptor in piglet saphenous vein

2. Prostaglandin E receptors

3. Therapeutic targets for urinary incontinence

4. Discovery of CP-533536: An EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation

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