Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference18 articles.
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3. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents;Hirai;Mol Cancer Ther,2009
4. AZD1775 increases sensitivity to olaparib and gemcitabine in cancer cells with p53 mutations;Meng;Cancers,2018
5. Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target;Aka;Int J Biochem Cell Biol,2021
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. An update on small molecule compounds targeting synthetic lethality for cancer therapy;European Journal of Medicinal Chemistry;2024-11
2. Advanced Design, Synthesis, and Evaluation of Highly Selective Wee1 Inhibitors: Enhancing Pharmacokinetics and Antitumor Efficacy;Journal of Medicinal Chemistry;2024-06-07
3. Insightful t-SNE guided exploration spotlighting Palbociclib and Ribociclib analogues as novel WEE1 kinase inhibitory candidates;Journal of Biomolecular Structure and Dynamics;2024-01-18
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