Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors

Published:2014-11 Issue:21 Volume:22 Page:6146-6155
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Yang Wei,Li Lixuan,Ji Xun,Wu Xiaowei,Su Mingbo,Sheng Li,Zang Yi,Li Jia,Liu Hong

Funder

National Natural Science Foundation of China

National S&T Major Projects

Chinese Academy of Science

National Science & Technology

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference51 articles.

1. HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics

2. Histone acetylation in chromatin structure and transcription

3. Chromatin Modifications and Their Function

4. Chromatin modification and epigenetic reprogramming in mammalian development

5. Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

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