Organocatalyzed umpolung addition for synthesis of heterocyclic-fused arylidene-imidazolones as anticancer agents
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference66 articles.
1. Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019;Newman;J Nat Prod,2020
2. “Scaffold-hopping” by topological pharmacophore search: a contribution to virtual screening;Schneider;Angew Chem Int Ed,1999
3. The scaffold hopping potential of pharmacophores;Hessler;Drug Discov Today Technol.,2010
4. Recent advances in scaffold hopping: miniperspective;Hu;J Med Chem.,2017
5. Scaffold hopping using two-dimensional fingerprints: true potential, black magic, or a hopeless endeavor? Guidelines for virtual screening;Vogt;J Med Chem.,2010
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