Design, synthesis and biological evaluation of imidazopyridazine derivatives containing isoquinoline group as potent MNK1/2 inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis and biological evaluation of imidazopyridazine derivatives containing isoquinoline group as potent MNK1/2 inhibitors

Published:2021-06 Issue: Volume:40 Page:116186
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Bu Hong,Yuan Xinrui,Wu Hanshu,Zhou Jinpei,Zhang Huibin

Funder

Jiangsu Province Natural Science Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. MNK1 and MNK2 mediate adverse effects of high-fat feeding in distinct ways;Moore;Sci Rep,2016

2. Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta;Slentz-Kesler;Genomics,2000

3. Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1;O'Loghlen;Exp Cell Res,2004

4. Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo;Waskiewicz;Mol Cell Biol,1999

5. Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2;Waskiewicz;EMBO J,1997

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development of an Imidazopyridazine-Based MNK1/2 Inhibitor for the Treatment of Lymphoma;Journal of Medicinal Chemistry;2024-04-02

2. Design, synthesis and biological evaluation of MNK-PROTACs;Molecular Diversity;2024-03-18

3. Design, synthesis and α-glucosidase inhibition study of novel pyridazin-based derivatives;Medicinal Chemistry Research;2023-02-15

4. Six-membered ring systems: pyridines and benzo derivatives;Progress in Heterocyclic Chemistry;2023

5. An Overview of the Biological Evaluation of Selected Nitrogen-Containing Heterocycle Medicinal Chemistry Compounds;International Journal of Molecular Sciences;2022-07-23

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