Synthesis, antimicrobial activity and molecular modeling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles-Reference-Cited by-同舟云学术

Synthesis, antimicrobial activity and molecular modeling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles

Published:2004-10 Issue:20 Volume:12 Page:5465-5483
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Menozzi Giulia,Merello Luisa,Fossa Paola,Schenone Silvia,Ranise Angelo,Mosti Luisa,Bondavalli Francesco,Loddo Roberta,Murgioni Chiara,Mascia Valeria,La Colla Paolo,Tamburini Elena

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference33 articles.

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2. Azole-antifungal binding to a novel cytochrome P450 from Mycobacterium tuberculosis : implications for treatment of tuberculosis 2 2Abbreviations: CYP, cytochrome P450; CYP51, lanosterol-14α-demethylase; MT, Mycobacterium tuberculosis and PCR, polymerase chain reaction.

3. Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes

4. Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis

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