Analysis of the binding sites of vitamin D 1α-hydroxylase (CYP27B1) and vitamin D 24-hydroxylase (CYP24A1) for the design of selective CYP24A1 inhibitors: Homology modelling, molecular dynamics simulations and identification of key binding requirements-Reference-Cited by-同舟云学术

Analysis of the binding sites of vitamin D 1α-hydroxylase (CYP27B1) and vitamin D 24-hydroxylase (CYP24A1) for the design of selective CYP24A1 inhibitors: Homology modelling, molecular dynamics simulations and identification of key binding requirements

Published:2017-10 Issue:20 Volume:25 Page:5629-5636
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Taban Ismail M.,Zhu Jinge,DeLuca Hector F.,Simons Claire^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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4. Vitamin D metabolism, mechanism of action, and clinical applications;Bikle;Chem Biol,2014

5. Regulation of target gene expression by the vitamin D receptor – an update on mechanisms;Pike;Rev Endocr Metab Disord,2012

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