Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel non-basic 1-(2H-indazole-5-yl)pyridin-2(1H)-one derivatives and mitigation of mutagenicity in Ames test-Reference-Cited by-同舟云学术

Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel non-basic 1-(2H-indazole-5-yl)pyridin-2(1H)-one derivatives and mitigation of mutagenicity in Ames test

Published:2016-06 Issue:11 Volume:24 Page:2504-2518
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Igawa Hideyuki,Takahashi Masashi,Ikoma Minoru,Kaku Hiromi,Kakegawa Keiko,Kina Asato,Aida Jumpei,Okuda Shoki,Kawata Yayoi,Noguchi Toshihiro,Hotta Natsu,Yamamoto Syunsuke,Nakayama Masaharu,Nagisa Yasutaka,Kasai Shizuo,Maekawa Tsuyoshi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference34 articles.

1. Anatomical organization of the melanin-concentrating hormone peptide family in the mammalian brain

2. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R

3. Increases in melanin-concentrating hormone and MCH receptor levels in the hypothalamus of dietary-obese rats

4. A role for melanin-concentrating hormone in the central regulation of feeding behaviour

5. Effects of Leptin on Melanin-Concentrating Hormone Expression in the Brain of Lean and Obese Lep^ob/Lep^ob Mice

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