Synthesis and biological evaluation of spirocyclic antagonists of CCR2 (chemokine CC receptor subtype 2)-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of spirocyclic antagonists of CCR2 (chemokine CC receptor subtype 2)

Published:2015-07 Issue:14 Volume:23 Page:4034-4049
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Strunz Ann Kathrin,Zweemer Annelien J.M.,Weiss Christina,Schepmann Dirk,Junker Anna,Heitman Laura H.,Koch Michael,Wünsch Bernhard

Funder

IRTG

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. Chemokines in Innate and Adaptive Host Defense: Basic Chemokinese Grammar for Immune Cells

2. Pharmacological modulation of chemokine receptor function

3. The CCR2 receptor as a therapeutic target

4. Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5

5. Immune and Inflammatory Mechanisms of Atherosclerosis

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2. Synthesis of new 1,4‐ and 1,5‐disubstituted N ‐ethyl acetate and N ‐α‐butyro‐γ‐lactone alkylimidazole derivatives as N ‐acylhomoserine lactone analogs;Journal of Heterocyclic Chemistry;2021-09-14

3. A unique ligand‐steered strategy for CC chemokine receptor 2 homology modeling to facilitate structure‐based virtual screening;Chemical Biology & Drug Design;2021-01-16

4. Development of the First Potential Nonpeptidic Positron Emission Tomography Tracer for the Imaging of CCR2 Receptors;ChemMedChem;2020-11-23

5. Rh-Catalyzed Asymmetric Hydroaminomethylation of α-Substituted Acrylamides: Application in the Synthesis of RWAY;Organic Letters;2020-11-09

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