Selective alkylation of βII-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents-Reference-Cited by-同舟云学术

Selective alkylation of βII-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents

Published:2008-08 Issue:15 Volume:16 Page:7277-7290
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Fortin Jessica S.,Côté Marie-France,Lacroix Jacques,Desjardins Michel,Petitclerc Éric,C.-Gaudreault René

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference44 articles.

1. 1-Aryl-3-(2-chloroethyl) Ureas: Synthesis and In Vitro Assay as Potential Anticancer Agents

2. Lack of cross-resistance to a new cytotoxic arylchloroethyl urea in various drug-resistant tumor cells

3. Alkylation of β-Tubulin on Glu 198 by a Microtubule Disrupter

4. Antiangiogenic and Antitumoral Activity of Phenyl-3-(2-Chloroethyl)Ureas

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Inhibition of nuclear thioredoxin aggregation attenuates PM2.5-induced NF-κB activation and pro-inflammatory responses;Free Radical Biology and Medicine;2019-01

2. Synthesis and Preliminary Cytotoxicity Studies of 1-[1-(4,5-Dihydrooxazol- 2-yl)-1H-indazol-3-yl]-3-phenylurea and 3-phenylthiourea Derivatives;Medicinal Chemistry;2017-10-17

3. Design, Synthesis and Anticancer Biological Evaluation of Novel 1,4-Diaryl- 1,2,3-triazole Retinoid Analogues of Tamibarotene (AM80);Journal of the Brazilian Chemical Society;2017

4. Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress;Free Radical Biology and Medicine;2013-12

5. Synthesis, Biological Evaluation, and Structure–Activity Relationships of Novel Substituted N-Phenyl Ureidobenzenesulfonate Derivatives Blocking Cell Cycle Progression in S-Phase and Inducing DNA Double-Strand Breaks;Journal of Medicinal Chemistry;2012-06-21