Structure–activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A1 adenosine receptor-Reference-Cited by-同舟云学术

Structure–activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A1 adenosine receptor

Published:2012-01 Issue:2 Volume:20 Page:996-1007
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Romagnoli Romeo,Baraldi Pier Giovanni,Carrion Maria Dora,Cara Carlota Lopez,Cruz-Lopez Olga,Salvador Maria Kimatrai,Preti Delia,Tabrizi Mojgan Aghazadeh,Shryock John C.,Moorman Allan R.,Vincenzi Fabrizio,Varani Katia,Borea Pier Andrea

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

1. Adenosine receptors as therapeutic targets

2. Preliminary Efficacy Assessment of Intrathecal Injection of an American Formulation of Adenosine in Humans

3. Allosteric Modulation of the Adenosine Family of Receptors

4. Allosteric Modulation of G Protein-Coupled Receptors

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