Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β)-Reference-Cited by-同舟云学术

Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β)

Published:2018-11 Issue:20 Volume:26 Page:5479-5493
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Gao Yang,Zhang Peng,Cui Anfeng,Ye De-Yong,Xiang Meng,Chu Yong

Funder

National Natural Science Foundation of China

School of Pharmacy, Fudan University

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference33 articles.

1. Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer;Zhang;Oncogene,2011

2. A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells;Tullai;Cell Cycle,2011

3. GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis;Wang;Cancer Cell,2010

4. Post-transcriptional regulation of cadherin-11 expression by GSK-3 and β-catenin in prostate and breast cancer cells;Farina;PLoS One,2009

5. Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells;Huang;Immunology,2009

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