Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group-Reference-Cited by-同舟云学术

Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group

Published:2006-12 Issue:23 Volume:14 Page:7761-7773
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Sirisoma Nilantha,Kasibhatla Shailaja,Nguyen Bao,Pervin Azra,Wang Yang,Claassen Gisela,Tseng Ben,Drewe John,Cai Sui Xiong

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. Drug discovery opportunities from apoptosis research

2. Neuroprotection by the Inhibition of Apoptosis

3. Dysregulation of Apoptosis in Cancer

4. Protease Inhibitors: Current Status and Future Prospects

5. Caspases: key mediators of apoptosis

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