Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET-Reference-Cited by-同舟云学术

Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET

Published:2006-02 Issue:4 Volume:14 Page:1115-1125
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Dollé Frédéric,Emond Patrick,Mavel Sylvie,Demphel Stéphane,Hinnen Françoise,Mincheva Zoïa,Saba Wadad,Valette Heric,Chalon Sylvie,Halldin Christer,Helfenbein Julie,Legaillard Joël,Madelmont Jean-Claude,Deloye Jean-Bernard,Bottlaender Michel,Guilloteau Denis

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference92 articles.

1. Mapping cocaine binding sites in human and baboon brain in vivo

2. Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism

3. In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [11C]WIN 35,428

4. Synthesis of a radiotracer for studying dopamine uptake sites in vivo using PET: 2β-carbomethoxy-3β-(4-fluorophenyl)-[N-11C-methyl]tropane ([11C]CFT or [11C]WIN-35,428)

5. Substituted 3-phenyltropane analogs of cocaine: synthesis, inhibition of binding at cocaine recognition sites, and positron emission tomography imaging

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2. Usefulness of PET With [18F]LBT-999 for the Evaluation of Presynaptic Dopaminergic Neuronal Loss in a Clinical Environment;Frontiers in Neurology;2020-08-21

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