Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types-Reference-Cited by-同舟云学术

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Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types

Published:2019-01 Issue:1 Volume:27 Page:208-215
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

De La Chapa Jorge,Valdez Matthew,Ruiz Franscisco,Gonzales Keith,Mitchell Wes,McHardy Stanton F.,Hart Matthew,Polusani Srikanth R.,Gonzales Cara B.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. Vanilloids induce oral cancer apoptosis independent of TRPV1

2. The Discovery of Capsazepine, the First Competitive Antagonist of the Sensory Neuron Excitants Capsaicin and Resiniferatoxin

3. Drug-like properties and the causes of poor solubility and poor permeability

4. An Efficient Parallel Synthesis of Capsazepine and Capsazepine Analogs

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1. Design and experimental validation of a new radiolabeled analog of N-(3-hydroxy-4-methoxy-phenyl-methyl) ferrocene-carboxamide (VFC) targeting the TRPV1 receptor;European Journal of Medicinal Chemistry Reports;2024-12

2. Bioelectric pharmacology of cancer: A systematic review of ion channel drugs affecting the cancer phenotype;Progress in Biophysics and Molecular Biology;2024-09

3. Capsaicin Ameliorates Chemotherapy Response via Cancer Hallmarks Modulation: An Overview of its Synergic Potential;Journal of Herbal Medicine;2024-06

4. Transient receptor potential channels’ genes forecast cervical cancer outcomes and illuminate its impact on tumor cells;Frontiers in Genetics;2024-05-09

5. Capsaicin derivatives: Synthesis and biological activity;Chemical Biology & Drug Design;2024-02

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