Discovery of 4-[4-({(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride: A highly potent orally available CCR5 selective antagonist

Author:

Nishizawa Rena,Nishiyama Toshihiko,Hisaichi Katsuya,Minamoto Chiaki,Murota Masayuki,Takaoka Yoshikazu,Nakai Hisao,Tada Hideaki,Sagawa Kenji,Shibayama Shiro,Fukushima Daikichi,Maeda Kenji,Mitsuya Hiroaki

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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