Development of versatile solid-phase methods for syntheses of PROTACs with diverse E3 ligands
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference22 articles.
1. PROTACs: past, present and future;Li;Chem Soc Rev,2022
2. E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points;Bricelj;Front Chem,2021
3. Target and tissue selectivity of PROTAC degraders;Guenette;Chem Soc Rev,2022
4. A practical “preTACs-cytoblot” platform accelerates the streamlined development of PROTAC-based protein degraders;Rao;Eur J Med Chem,2023
5. Chemical methods for peptide and protein production;Chandrudu;Molecules,2013
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1. Expansion of targeted degradation by Gilteritinib-Warheaded PROTACs to ALK fusion proteins;Bioorganic Chemistry;2024-04
2. Journey of Von Hippel-Lindau (VHL) E3 ligase in PROTACs design: From VHL ligands to VHL-based degraders;European Journal of Medicinal Chemistry;2024-02
3. Current advances and development strategies of orally bioavailable PROTACs;European Journal of Medicinal Chemistry;2023-12
4. Solid‐Phase Synthesis of PROTACs and SNIPERs on Backbone Amide Linked (BAL) Resin;Chemistry – A European Journal;2023-09-07
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