Synthesis of new derivatives of 21-imidazolyl-16-dehydropregnenolone as inhibitors of 5α-reductase 2 and with cytotoxic activity in cancer cells-Reference-Cited by-同舟云学术

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Synthesis of new derivatives of 21-imidazolyl-16-dehydropregnenolone as inhibitors of 5α-reductase 2 and with cytotoxic activity in cancer cells

Published:2017-03 Issue:5 Volume:25 Page:1600-1607
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Silva-Ortiz Aylin Viviana,Bratoeff Eugene,Ramírez-Apan Teresa,Heuze Yvonne,Soriano Juan,Moreno Isabel,Bravo Marisol,Bautista Lucero,Cabeza Marisa

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference39 articles.

1. Differential alterations in 5?-reductase type 1 and type 2 levels during development and progression of prostate cancer

2. STEROID 5α-REDUCTASE: TWO GENES/TWO ENZYMES

3. Cytochrome P-45017α in β-cells of rat pancreas and its local steroidogenesis

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1. Steroidal 21-imidazolium salt derivatives: Synthesis and anticancer activity;Steroids;2024-10

2. Steroidal 21-Imidazolium Salt Derivatives: Synthesis and Antitumoral Activity;2024

3. Oxazolinyl derivatives of androst-16-ene as inhibitors of CYP17A1 activity and prostate carcinoma cells proliferation: Effects of substituents in oxazolinyl moiety;The Journal of Steroid Biochemistry and Molecular Biology;2023-06

4. A Medicinal Chemist’s Perspective Towards Structure Activity Relationship of Heterocycle Based Anticancer Agents;Current Topics in Medicinal Chemistry;2022-03

5. Novel Nitrogen Containing Steroid Derivatives for Prostate Cancer Treatment;Current Medicinal Chemistry;2021-12

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