Synthesis and biological evaluation of 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins as potent NADPH oxidase (NOX) inhibitors-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins as potent NADPH oxidase (NOX) inhibitors

Published:2016-09 Issue:18 Volume:24 Page:4144-4151
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Bae Yun Soo,Choi Sun,Park Jung Jae,Joo Jung Hee,Cui Minghua,Cho Hyunsung,Lee Won Jae,Lee Sang Hyup

Funder

National Research Foundation of Korea

Ministry of Education, Science and Technology

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Antimycobacterial activity of 5-arylidene derivatives of hydantoin

2. SYNTHESIS, REACTIONS AND CONFORMATIONAL ANALYSIS OF 5-ARYLIDENE-2-THIOHYDANTOINS AS POTENTIAL ANTIVIRAL AGENTS

3. Potential anticonvulsants. 1. 5-Benzylhydantoins

4. Isolation, synthesis and antitumor evaluation of spirohydantoin aziridine, a mutagenic metabolite of spirohydantoin mustard

5. NADPH Oxidases in Cardiovascular Health and Disease

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2. 3‐aminohydantoin derivate as a promising scaffold in dopaminergic neuroprotection and neurorescue in the in vivo and in vitro 6‐hydroxydopamine models of Parkinson's disease;Clinical and Experimental Pharmacology and Physiology;2023-06-18

3. Synthesis of bis-thiohydantoin derivatives as an antiproliferative agents targeting EGFR inhibitory pathway;Molecular Diversity;2023-06-12

4. Discovery of a NADPH oxidase inhibitor, (E)-3-cyclohexyl-5-(4-((2-hydroxyethyl)(methyl)amino)benzylidene)-1-methyl-2-thioxoimidazolidin-4-oneone, as a novel therapeutic for Parkinson's disease;European Journal of Medicinal Chemistry;2022-12

5. One-pot high-throughput synthesis of N3-substituted 5-arylidene-2-thiohydantoin amides and acids;Tetrahedron Letters;2022-08

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