Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability-Reference-Cited by-同舟云学术

Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability

Published:2022-02 Issue: Volume:56 Page:116588
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Williams Jordan,Siramshetty Vishal,Nguyễn Ðắc-Trung,Padilha Elias Carvalho,Kabir Md.,Yu Kyeong-Ri,Wang Amy Q.,Zhao Tongan,Itkin Misha,Shinn Paul,Mathé Ewy A.,Xu Xin,Shah Pranav

Funder

National Center for Advancing Translational Sciences

National Institutes of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference67 articles.

1. Logistic Classification Models for pH-Permeability Profile: Predicting Permeability Classes for the Biopharmaceutical Classification System;Oja;J Chem Inf Model,2019

2. The Permeability of an Artificial Membrane for Wide Range of pH in Human Gastrointestinal Tract: Experimental Measurements and Quantitative StructureActivity Relationship;Oja;Mol Inf,2015

3. Drug-permeability and transporter assays in Caco-2 and MDCK cell lines;Volpe;Future Med Chem,2011

4. Regional intestinal drug permeation: biopharmaceutics and drug development;Lennernas;Eur J Pharm Sci,2014

5. Regional Intestinal Permeability of Three Model Drugs in Human;Dahlgren;Mol Pharm,2016

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