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Design, synthesis and evaluation of the osimertinib analogue (C-005) as potent EGFR inhibitor against NSCLC

  • Published:2018-12 Issue:23-24 Volume:26 Page:6135-6145
  • ISSN:0968-0896
  • Container-title:Bioorganic & Medicinal Chemistry
  • language:en
  • Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Zhou Ping,Chen Gang,Gao Minqi,Wu Jiaquan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference44 articles.

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3. New technologies in epidermal growth factor receptor targeted cancer therapy;Baselga;Signal,2000

4. Epidermal growth factor-related peptides and their receptors in human malignancies;Salomon;Crit Rev Oncol Hematol,1995

5. EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities;The;Eur J Cancer,2001

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