Design, synthesis and bioactivity evaluation of a series of quinazolinone derivatives as potent PI3Kγ antagonist-Reference-Cited by-同舟云学术

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Design, synthesis and bioactivity evaluation of a series of quinazolinone derivatives as potent PI3Kγ antagonist

Published:2023-04 Issue: Volume:84 Page:117261
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Liang Yuqing,Zheng Yanjun,Yang Junjie,Ke Jiahua,Cheng Kui

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangzhou Science and Technology Program key projects

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. Next generation of immune checkpoint inhibitors and beyond;Marin-Acevedo;J Hematol Oncol.,2021

2. A decade of immune-checkpoint inhibitors in cancer therapy;Robert;Nat Commun.,2020

3. Small molecule immunomodulation: the tumor microenvironment and overcoming immune escape;Osipov;J Immunother Cancer.,2019

4. PD-1 blockade in tumors with mismatch-repair deficiency;Le;N Engl J Med.,2015

5. The Next Generation of Immunotherapy for Cancer: Small Molecules Could Make Big Waves;Kerr;J Immunol.,2019

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Designing Small Molecule PI3Kγ Inhibitors: A Review of Structure-Based Methods and Computational Approaches;Journal of Medicinal Chemistry;2024-06-19

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