Design, synthesis and anticancer activity evaluation of 4-(3-1H-indazolyl)amino quinazoline derivatives as PAK4 inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis and anticancer activity evaluation of 4-(3-1H-indazolyl)amino quinazoline derivatives as PAK4 inhibitors

Published:2023-11 Issue: Volume:95 Page:117501
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Han Wei,Yang Yusang,Yu Fan,Li Qianqian,Liu Anyao,Xu Wenbo,Li Jiabin,Xue Xiaowen

Funder

China Pharmaceutical University

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference38 articles.

1. Rudolph J, Crawford JJ, Hoeflich KP, Chernoff J. p21-Activated kinase inhibitors. Enzymes. 2013;34 Part B:157−180. https://doi.org/10.1016/B978-0-12-420146-0.00007-X.

2. P21 activated kinase signaling in cancer;Rane;Semin Cancer Biol,2019

3. A tale of two Paks;Arias-Romero;Biol Cell,2008

4. PAK signalling during the development and progression of cancer;Radu;Nat Rev Cancer,2014

5. CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating beta-catenin/MEK-ERK signaling pathway;Huang;Cell Death Differ,2022

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1. Synthesis of 2‐phenylnaphthalenoid amide derivatives and their topoisomerase IIα inhibitory and antiproliferative activities;Archiv der Pharmazie;2024-06-23

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