Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase-Reference-Cited by-同舟云学术

Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase

Published:2013-07 Issue:14 Volume:21 Page:4218-4224
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Zhu Jinmei,Wu Chun-Feng,Li Xiaobing,Wu Gui-Sheng,Xie Shan,Hu Qian-Nan,Deng Zixin,Zhu Michael X.,Luo Huai-Rong,Hong Xuechuan

Funder

National Science and Technology Major Project of the Ministry of Science and Technology of China

Key Project of Chinese Ministry of Education

Specialized Research Fund of the Doctoral Program of Higher Education

Fundamental Research Funds for the Central Universities

National Mega Project on Major Drug Development

Yunnan provincial government

Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. The Cost of Dementia in Europe

2. A prion protein connection

3. Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors

4. The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals

5. Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies

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