Discovery of potent sulfonamide P4-capped ketoamide second generation inhibitors of hepatitis C virus NS3 serine protease with favorable pharmacokinetic profiles in preclinical species-Reference-Cited by-同舟云学术

Discovery of potent sulfonamide P4-capped ketoamide second generation inhibitors of hepatitis C virus NS3 serine protease with favorable pharmacokinetic profiles in preclinical species

Published:2010-03 Issue:5 Volume:18 Page:1854-1865
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Bogen Stéphane L.,Arasappan Ashok,Velazquez Francisco,Blackman Melissa,Huelgas Regina,Pan Weidong,Siegel Elise,Nair Latha G.,Venkatraman Srikanth,Guo Zhuyan,Doll Ronald,Shih Neng-Yang,George Njoroge F.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference56 articles.

1. World health organization Fact sheet number 164, October 2000.

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5. Mechanism of action of interferon and ribavirin in treatment of hepatitis C

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