Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α-Reference-Cited by-同舟云学术

Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α

Published:2021-01 Issue: Volume:30 Page:115949
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Shimizu Takahiro,Takahashi Norihito,Huber Vincent J.,Asawa Yasunobu,Ueda Hiroki,Yoshimori Atsushi,Muramatsu Yukiko,Seimiya Hiroyuki,Kouji Hiroyuki,Nakamura Hiroyuki,Oguri Hiroki

Funder

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference58 articles.

1. Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes

2. Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

3. Protein Domain Mimics as Modulators of Protein–Protein Interactions

4. Inhibition of α-helix-mediated protein–protein interactions using designed molecules

5. The coactivator LXXLL nuclear receptor recognition motif

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