Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors

Published:2014-02 Issue:4 Volume:22 Page:1441-1449
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Kusuma Bhaskar Reddy,Khandelwal Anuj,Gu Wen,Brown Douglas,Liu Weiya,Vielhauer George,Holzbeierlein Jeffrey,Blagg Brian S.J.

Funder

NIH/NCI

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference50 articles.

1. Hsp90 as a Target for Drug Development

2. Hsp90: A Novel Target for the Disruption of Multiple Signaling Cascades

3. Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors

4. Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

5. HSP90 and the chaperoning of cancer

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5. Ligand-based pharmacophore modelling, structure optimisation, and biological evaluation for the identification of 2-heteroarylthio- N -arylacetamides as novel HSP90 C-terminal inhibitors;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-12-11

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