Conformational analysis of two novel cytotoxic C2-substituted pyrrolo[2,3-f]quinolines in aqueous media, organic solvents, membrane bilayers and at the putative active site-Reference-Cited by-同舟云学术

Conformational analysis of two novel cytotoxic C2-substituted pyrrolo[2,3-f]quinolines in aqueous media, organic solvents, membrane bilayers and at the putative active site

Published:2012-11 Issue:21 Volume:20 Page:6276-6284
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Varvarigou Nicole,Megariotis Grigorios,Leonis Georgios,Vrontaki Eleni,Maniati Antigoni-Margarita,Vlachou Marilena,Eikosipentaki Aphrodite,Kompogennitaki Rodanthi,Papadopoulos Manthos G.,Grdadolnik Simona Golic,Komiotis Dimitri,Mavromoustakos Thomas,Tsotinis Andrew

Funder

European Commission

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference36 articles.

1. Sequence preferences of DNA interstrand crosslinking agents: quantitation of interstrand crosslink locations in DNA duplex fragments containing multiple crosslinkable sites

2. Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring system

3. A Facile Synthesis of C2-Substituted Pyrrolo[2,3-f]quinolines with Cytotoxic Activity

4. Symmetrical Derivatives of C2-Substituted Pyrrolo[2,3-f]quinolines:Synthesis, Cytotoxicity and Drug Delivery Studies

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