Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin-Reference-Cited by-同舟云学术

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Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin

Published:2014-04 Issue:7 Volume:22 Page:2339-2352
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Teno Naoki,Gohda Keigo,Wanaka Keiko,Tsuda Yuko,Sueda Takuya,Yamashita Yukiko,Otsubo Tadamune

Funder

Ministry of Education, Science, Sports and Culture of Japan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. The plasminogen-plasmin system in malignancy

2. Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b+/F4/80+ myeloid cell recruitment

3. Plasminogen activation and cancer

4. Plasmin Substrate Binding Site Cooperativity Guides the Design of Potent Peptide Aldehyde Inhibitors

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1. Bicyclic 5-6 Systems: Three Heteroatoms 1:2;Comprehensive Heterocyclic Chemistry IV;2022

2. Different addition modes of cyclopentadiene and furan at methylidene(thio)hydantoins;Mendeleev Communications;2021-03

3. Synthesis of a novel phenytoin derivative: Crystal structure, Hirshfeld surface analysis and DFT calculations;Journal of Molecular Structure;2020-04

4. Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding;Journal of Medicinal Chemistry;2019-10-28

5. Recent applications of hydantoin and thiohydantoin in medicinal chemistry;European Journal of Medicinal Chemistry;2019-02

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