New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor-Reference-Cited by-同舟云学术

New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor

Published:2011-05 Issue:10 Volume:19 Page:3074-3085
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Guerrini Gabriella,Ciciani Giovanna,Bruni Fabrizio,Selleri Silvia,Melani Fabrizio,Daniele Simona,Martini Claudia,Costanzo Annarella

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference33 articles.

1. The complexity of the GABAA receptor shapes unique pharmacological profiles

2. International Union of Pharmacology. LXX. Subtypes of γ-Aminobutyric AcidAReceptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

3. A nomenclature for ligand-gated ion channels

4. Analysis of GABAA Receptor Function and Dissection of the Pharmacology of Benzodiazepines and General Anesthetics Through Mouse Genetics

5. GABA-based therapeutic approaches: GABAA receptor subtype functions

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